Human Rhesus macaque CD27 / TNFRSF7 Recombinant Protein Mouse IgG Fc Tag Lyophilized from Innovative Research has been recombinantly produced in HEK293 cells. This is a Lyophilized protein buffered in 50 mM Tris, 100 mM Glycine, pH7.5 with a purity of >95% as determined by SDS-PAGE..
More Details:
- Species: Human
- Target: CD27
- Purity: >95% as determined by SDS-PAGE.
- Source: HEK293 cells
- Storage Conditions: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Additional Information:
CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-?B and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
This protein carries a mouse IgG2a Fc Tag at the C-terminal. The protein has a calculated MW of 46.2 kDa. The protein migrates as 50-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.